
A road trip from Jacksonville to Key West covers nearly 600 miles of Florida sunshine, weaving together riverfront neighborhoods, sandy Atlantic beaches, vibrant cities, and the island charm of the Keys.
Along the way you’ll hit Orlando’s theme parks, stroll stylish coastal spots like Boca Raton and Fort Lauderdale, dive into Miami’s nonstop energy, and end with the slow, easy pace of Key West.
Think of this guide as your roadmap to the best stops, the can’t-miss sights, and the little tips that make the journey smoother, and a lot more fun.
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Table of Contents
Planning the Drive
This itinerary from Jacksonville to Key West runs under 600 miles and takes roughly 9–10 hours of pure drive time, but that doesn’t mean you should tackle it all at once.
The sweet spot is spreading the trip across 10–12 days, giving yourself 1 to 3 nights at each stop. This way, you’ll actually enjoy Orlando’s theme parks instead of rushing through lines or have time to linger in Miami’s art districts instead of getting stuck in traffic.
To be on the safe side, designate a fuel budget between $90 and $120 for the full trip, depending on your vehicle’s mileage and Florida’s current gas prices. Building this into your budget will avoid surprises, especially if you’re renting a car.
Florida’s highways, I-95 and I-4, are notorious for traffic jams, with Orlando being a consistent hotspot.
Plan major drives outside of rush hours. Avoid driving between 7AM and 9AM and between 4PM and 6PM windows, use apps like Waze for real-time detours, and consider scenic byways when possible. A little flexibility in your timing can save you hours of frustration.
When to Go
Florida is a year-round destination, but winter and spring, especially the period between December and May are ideal. Summer brings the liveliest festivals and the warmest waters, but also higher humidity, afternoon thunderstorms, and bigger crowds.
If you are traveling in late summer or fall, check forecasts before you set out. Most storms are short-lived, and Florida is used to sudden showers. Pack a light rain jacket or poncho, you’ll often find the sun shining again within an hour.
Theme parks and beaches can feel overrun during school holidays.
Visit parks mid-week, arrive right at opening, and reserve tickets online to save money and avoid last-minute sold-out days. For beaches, mornings and late afternoons are less crowded.
What to Pack
Packing smart can make the difference between a breezy Florida road trip and one that feels like a juggling act. The state’s sunshine is intense year-round, so sunscreen and a wide-brimmed hat are must-haves, even in the cooler months.
- Swimsuits and water shoes will come in handy whether you’re spending the day at the beach, lounging by the hotel pool, or heading out on a kayaking adventure.
- Florida weather has a reputation for changing on a dime, so light rain gear is also good to have. Afternoon showers often roll through in summer, but they usually pass quickly, being prepared means you won’t lose a whole day to the weather.
- Insect repellent is another item worth keeping in your day bag if you plan to visit the Everglades or spend time near marshes and trails.
- For long drives and theme park days, stock up on car snacks and bring reusable water bottles. This will keep everyone happy between stops, and you will avoid the sticker shock of theme park food, where even a bottle of water can feel overpriced.
- Parking lots at big attractions can mean a long walk back to the car, so it’s always easier to carry drinks and light snacks with you.
Travelers usually worry about airline baggage limits or airport security when packing for a trip like this.
The simple solution is to buy bulky items, like sunscreen, bottled water, or snacks, once you land. Florida is full of pharmacies, supermarkets, and convenience stores, and stocking up locally saves space in your luggage and also often costs less than buying these items at resort or attraction prices.
Kid-Friendly Tips
If you’re traveling with kids, balance big, high-energy days with slower downtime.
A day at Disney or Universal can be magical, but also exhausting with long lines, pricey tickets, and overstimulation. Follow it with a beach day, hotel pool time, or a short outing like a zoo visit.
Bring portable games, download movies on a tablet, and schedule mid-afternoon breaks. Many Sonesta hotels feature pools and spacious suites where kids can recharge.
Keeping drive times shorter between big attractions also makes the road trip smoother for everyone.

Jacksonville Beach, Jacksonville, Florida
Stop 1: Jacksonville – 1 Night
Kick off your trip in Jacksonville, a city of tree-lined avenues and sandy shores.
Start your day with a stroll through Riverside and Avondale, exploring unique boutiques, inviting cafés, and the easygoing charm of one of Jacksonville’s most beloved neighborhoods.
Continue to the Cummer Museum of Art & Gardens, a riverside gem with an impressive art collection and tranquil gardens along the St. Johns River.
For a classic coastal moment, head to the Jacksonville Beach Pier to catch sea breezes or a golden sunset. Adventurous travelers can swap the pier for a kayak trip on the St. Johns River.
Families will love the Jacksonville Zoo and Gardens, especially the splash pad for kids on warm afternoons.
For a seamless visit to Jacksonville, keep in mind:
- Traffic near bridges can back up during rush hour, so aim to arrive mid-day.
- Beach parking fills quickly on weekends, go early for the best spots.
Where to Stay in Jacksonville, FL
While Jacksonville is easy to navigate, staying just outside the city can mean more space, easier parking, and a quieter place to recharge ahead of your road trip.
These nearby Sonesta hotels keep you close to downtown with the added comfort and convenience road travelers appreciate.
Stop 2: Orlando – 3 Nights
No Florida road trip feels complete without a stop in Orlando, the state’s theme park capital.
With more attractions than you can fit into one visit, pacing is everything. Spending at least three nights gives you time to enjoy the big parks, explore quieter corners of the city, and still leave space to recharge.
Day 1: Walt Disney World® Resort
Begin your Orlando adventure at Walt Disney World® Resort, home to four major theme parks: Magic Kingdom® Park, EPCOT®, Disney’s Hollywood Studios®, and Disney’s Animal Kingdom® Theme Park.
A single-day ticket starts around $109 per adult and $104 per child, ages 3 to 9, with peak dates running higher. Parking adds about $30 per car.
Families often gravitate to Magic Kingdom® Park, while couples and groups might prefer EPCOT®’s international pavilions, wine tastings, and seasonal food festivals.
Disney’s Hollywood Studios® is another strong pick, especially for Star Wars fans eager to explore Star Wars: Galaxy’s Edge®.
To make the most of your visit:
- Arrive early for “rope drop” when crowds are lightest and ride times shortest.
- Consider Disney Genie+ for priority access on the most popular rides.
- Save money by packing your own snacks and refillable water bottles; food inside can be pricey.
- Expect afternoon heat, plan indoor shows or shaded breaks to recharge.
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Day 2: Universal Orlando Resort™ & Universal CityWalk™
Spend your second day in Orlando at Universal Orlando Resort™, which includes Universal Studios Florida™ and Universal’s Islands of Adventure™.
Thrill-seekers will love coasters like The Incredible Hulk Coaster® and Hollywood Rip Ride Rockit™, while couples and groups often linger in The Wizarding World of Harry Potter™ to sip Butterbeer™.
Tickets start at $119 per adult, or $174+ for a Park-to-Park pass that includes Hogwarts™ Express. Parking runs from $32 per vehicle.
After the parks close, head to Universal CityWalk™. Grab a drink at Pat O’Brien’s® with live dueling pianos, catch some music, or satisfy a late-night craving with a Voodoo Doughnut®. It’s the perfect way to keep the fun going. Entry is free.
Savvy travelers:
- Buy tickets online in advance for lower prices and to skip long lines at the gate.
- Arrive before 10AM for better parking and shorter waits on rides.
- If you want to ride everything, splurge on an Express Pass, it can save hours.
- Save CityWalk for dinner; parking after 6PM is often discounted or free (except event nights).
Day 3: Gardens, Winter Park, or LEGOLAND® Florida Resort
After two fast-paced park days, you’ll likely be ready to slow down. Nature lovers can explore Harry P. Leu Gardens, while couples might enjoy the romantic walking trails and butterfly gardens.
If you’re traveling with young children, LEGOLAND® Florida Resort in Winter Haven is a top choice for kids ages 2 to 12. Tickets start at $99 per adult, $84 per child, plus $27 for parking.
Orlando also has a vibrant cultural side. The Orlando Museum of Art, Dr. Phillips Center for the Performing Arts, and the Mills 50 district with its street art and bars are travelers’ favorites. Couples often enjoy a cocktail tour in downtown Orlando or rooftop drinks with city views.
For a seamless visit:
- Aim for mornings outdoors; afternoon heat and showers are common in summer.
- Bring bug spray if you’re visiting gardens or taking the boat tour.
- At LEGOLAND, the water park is a great way to cool off, so pack swimsuits and towels.
- For adults seeking nightlife, downtown Orlando is full of craft breweries, and live jazz clubs away from the theme park crowds.
Where to Stay in Orlando, FL
Stay close to top attractions, entertainment, and shopping at Sonesta hotels in Orlando, Florida.
Theme park thrills, dining, and family fun are all just a minutes away, with a comfortable and convenient home base to return to.

Lake Boca Raton, Boca Raton, Florida
Stop 3: Boca Raton – 1 Night
Boca Raton makes for a stylish overnight stop between Orlando and South Florida.
Explore Mizner Park, an open-air plaza filled with restaurants, boutique shops, and a lively amphitheater that often hosts concerts. Nature lovers will find sea turtle exhibits, a butterfly garden, and peaceful boardwalk trails to explore at the Gumbo Limbo Nature Center.
Soak up the sun at Red Reef Park, a beach with calm waters that’s also home to an offshore artificial reef, ideal for snorkeling. Families can detour to the Children’s Science Explorium at Sugar Sand Park for interactive exhibits.
Some tips to keep in mind:
- Parking near the beach is limited, so arrive early to secure a spot.
- Mizner Park is busiest on weekends, so plan for extra time if dining during peak hours.
- Entry to Gumbo Limbo is free, though donations are suggested.
- If you plan to snorkel, pack reef-safe sunscreen and water shoes.
Where to Stay in Boca Raton, FL
For travelers looking to slow the pace between big city stops, stay at one of Sonesta stylish and relaxing hotels in Boca Raton, right off I-95.

Fort Lauderdale Beach, Fort Lauderdale, Florida
Stop 4: Fort Lauderdale – 2 Nights
With golden beaches and a nightlife that rivals Miami, Fort Lauderdale deserves more than a quick stop.
Two nights here gives you the chance to enjoy both relaxed daytime exploring and lively evenings along the coast.
Day 1: Beachfront & Bonnet House
Stroll along the Fort Lauderdale Beach promenade, a palm-lined stretch that’s ideal for long walks, bike rides, or simply enjoying the views of the Atlantic.
If you’d rather relax, spread out on the sandy beach or rent loungers for the day.
In the afternoon, explore the Bonnet House Museum & Gardens, a 1920s estate filled with art, antiques, and tropical landscapes that feels like a hidden retreat just minutes from the shoreline. Bonnet House tickets can be purchased online.
Parking near the beach fills quickly, so arrive before 10AM or use a garage a few blocks inland.
Day 2: Waterways & Las Olas
Fort Lauderdale’s nickname, the “Venice of America,” comes alive when you board the water taxi along the Intracoastal Waterway. A day pass costs about $35 for adults and $15 for kids, and allows unlimited hop-on, hop-off stops at waterfront restaurants, shops, and inspiring neighborhoods.
Spend the evening on Las Olas Boulevard, lined with rooftop bars, cocktail lounges, and upscale dining. Families can opt for the Museum of Discovery and Science, which features hands-on exhibits and an IMAX theater.
To make the most of this visit:
- Bring sunscreen and a hat for the water taxi, as seating on the upper deck, it is sunny but has the best views.
- Las Olas restaurants get busy on weekends, so reservations are recommended.
- The Museum of Discovery and Science costs about $30 for adults, $25 for kids, and is a great rainy-day backup.
Where to Stay in Fort Lauderdale, FL
Fort Lauderdale is best enjoyed at a relaxed pace, and staying close to the action makes your visit that much easier. Spend your days on the beach, cruising the Intracoastal, or exploring the shops and restaurants along Las Olas Boulevard.
Sonesta has convenient Fort Lauderdale stays right in the heart of it all.

View of Port of Miami, Miami, Florida
Stop 5: Miami – 3 Nights
It’s the city of sun-drenched beaches, bold art, world-class dining, and a nightlife scene that doesn’t sleep.
Three nights in Miami give you enough time to balance the iconic spots such as South Beach, Little Havana, and Wynwood, with quieter moments in museums, gardens, or natural parks nearby.
Day 1: South Beach & Art Deco District
Begin your tour with Miami’s most famous stretch: South Beach. The white sand, turquoise waters, and iconic lifeguard towers invite you to spend your morning swimming, sunbathing, or people-watching.
Stroll along Ocean Drive to admire the pastel-toned Art Deco District, lined with 1930s hotels and neon-lit façades.
After dark, cool off in a rooftop pool or grab a cocktail along Collins Avenue. Bright lights, bold flavors, and breezy vibes keep the energy going long after sunset.
Keep in mind:
- Parking in South Beach can be expensive, often between $20 to $40 per day; consider using a rideshare to avoid the hassle.
- The beach gets crowded by midday, arrive early for a quieter stretch and easier parking.
- Bring cash for café tips and street vendors; some smaller spots don’t accept cards.
Day 2: Wynwood Walls, Little Havana & Pérez Art Museum
Trade the beach for a dose of culture with a morning in Wynwood, Miami’s vibrant arts district. Wander through the Wynwood Walls, an open-air museum of bold street murals by artists from around the globe, then grab coffee or a local brew at one of the neighborhood’s laid-back spots.
In the afternoon, head to Little Havana, the heart of Miami’s Cuban community. Visit Little Havana mid-afternoon, it’s quieter than evenings but still lively.
Stroll down Calle Ocho, watch a game of dominoes at Máximo Gómez Park, and be sure to sample some Cuban staples such as ropa vieja, empanadas, and of course, Cuban coffee.
Wrap up the day at the Pérez Art Museum Miami (PAMM), a contemporary museum perched on Biscayne Bay. Thursdays at PAMM are often free or discounted, so be sure to check their schedule before visiting.
Day 3: Day Trip to Everglades National Park
Use your final day in Miami for an escape into nature at the Everglades National Park, about 45-60 minutes west of downtown Miami in regular traffic conditions. Airboat tours skim across wetlands where you can easily spot alligators, turtles, and wading birds.
If you prefer to explore on foot, the Anhinga Trail is an easy walk that feels worlds away, with wildlife often just steps from the boardwalk.
Families can kick off the day at the Miami Children’s Museum, where hands-on play zones, climbing areas, and colorful exhibits turn learning into all-day fun.
For a seamless, fun visit to the Everglades National Park:
- Bring bug spray, sunscreen, and a hat for the Everglades, it can get hot and buggy.
- If you’re visiting in summer, go early in the morning before the storms roll in.
- Book airboat rides in advance during high season.
Where to Stay in Miami, FL
For visitors exploring Miami, staying close to the action makes all the difference. Sonesta hotels in Miami put you near the beaches, shopping, dining, and nightlife with easy access to parking and top attractions across the city.

Port at Key West, Florida
Stop 6: Key West – 1 Night
End your road trip in Key West, the southernmost point of the continental U.S.
Stop by the Ernest Hemingway Home & Museum, where six-toed cats still roam the grounds of the famous writer’s former home. Tickets for the Hemingway House cost around $18 per adult and $7 for children.
As the sun sets, head to Mallory Square for lively street performers, local bites, and unbeatable ocean views. Parking can be scarce near Mallory Square, so it is recommended to arrive early or use a local shuttle.
If you have a little extra time, snap a photo at the iconic Southernmost Point marker or hop on a sunset cruise to end your trip on the water.
For a hands-on marine adventure, families can visit the Key West Aquarium, one of the island’s oldest attractions. The Key West Aquarium charges $22.56 per adult, $17.06 per child as of 2025.
Discover Florida & Stay Smarter with Sonesta Travel Pass
With Sonesta hotels at key stops along the route, the Sonesta Travel Pass loyalty program adds extra value to your stay.
Members earn points toward free nights and enjoy exclusive rates, room upgrades, and other tier-based perks like late checkout and bonus point multipliers. It’s free to join and worth considering if you’re planning more than just one trip.

Sonesta Simply Suites Jacksonville
4990 Belfort Road
Jacksonville, FL 32256
Extended-stay hotel in Jacksonville offering spacious suites with full kitchens and a convenient location near shopping, dining, and major highways ideal for longer stays or quick getaways.

Sonesta ES Suites Orlando - International Drive
8480 International Drive
Orlando, FL 32819
Located on International Drive, this residential-style, family-friendly hotel features full kitchens, a relaxing pool, and convenient access to Orlando’s top theme parks, dining, and entertainment.

Sonesta Essential Orlando Airport
8101 Aircenter CT
Orlando, FL 32809
Just minutes from Orlando’s world-famous theme parks, this comfortable and convenient stay features modern rooms, a pool, and everything you need for a hassle-free family getaway.

Sonesta Select Boca Raton Town Center
2000 NW Executive Center Circle
Boca Raton, FL 33431
Tucked in a peaceful Boca Raton neighborhood, this modern stay features spacious rooms, a pool, and easy access to beaches, shopping, and local dining.

Sonesta Fort Lauderdale Beach
999 N Fort Lauderdale Beach Blvd
Fort Lauderdale, FL 33304
Set on a quiet stretch of Fort Lauderdale Beach, this oceanfront stay features modern rooms with sweeping views, upscale amenities and easy access to local shops, restaurants, and waterfront fun.

Sonesta ES Suites Fort Lauderdale Plantation
410 North Pine Island Road
Plantation, FL 33324
This family-friendly, all-suite hotel is ideal for extended stays, with spacious layouts, full kitchens, free breakfast, and easy access to beaches, shopping, and downtown Fort Lauderdale.

Nautilus Sonesta Miami Beach
1825 Collins Ave
Miami Beach, FL 33139
Steps from the sand in South Beach, this oceanfront retreat pairs Art Deco charm with modern style, featuring a saltwater pool, ocean views, and a front-row seat to Miami’s vibrant energy.

Sonesta Simply Suites Miami Airport Doral
8855 NW 27th St.
Miami, FL 33172
A family-friendly, extended-stay hotel with spacious suites and convenient amenities with easy access to shopping, dining, and downtown Miami adventures.
Disclaimer: The suggested itinerary and points of interest are provided for informational and planning purposes only. Guests are encouraged to independently verify opening hours, availability, travel times, and any potential changes prior to visiting. The inclusion of any businesses, attractions, or destinations does not imply affiliation with or endorsement by Sonesta or its affiliates. Sonesta makes no representations or warranties regarding the accuracy or completeness of the information provided and assumes no responsibility for any inconvenience or loss arising from the use of this information.